{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316206/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316206"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Impact of Mettl1 on the transcriptional landscape of mouse bone marrow cells at single-cell resolution [scRNA-seq]","description":"This study investigates the impact of Mettl1 deletion on the transcriptional landscape of bone marrow cells at single-cell resolution. Bone marrow mononuclear cells (BM MNCs) were collected from Mettl1+/+ Mx1-Cre and Mettl1fl/fl Mx1-Cre mice following poly(I:C)-induced recombination. Single-cell RNA sequencing (scRNA-seq) was performed using the 10x Genomics Chromium platform. The resulting data were used to identify distinct cell populations, and assess transcriptional changes associated with Mettl1 loss. This dataset provides a valuable resource for understanding the role of Mettl1 in normal hematopoiesis.","dates":{"publication":"2026/07/29"},"accession":"GSE316206","cross_references":{"GSM":["GSM9447351","GSM9447352"],"GPL":["34328"],"GSE":["316206"],"taxon":["Mus musculus"],"PMID":["[42247311]"]}}