<HashMap><database>GEO</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Other>ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316278/</Other></files><type>primary</type></body><statusCode>OK</statusCode><statusCodeValue>200</statusCodeValue></file_versions><scores/><additional><omics_type>Transcriptomics</omics_type><species>Mus musculus</species><gds_type>Expression profiling by high throughput sequencing</gds_type><full_dataset_link>https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316278</full_dataset_link><repository>GEO</repository><entry_type>GSE</entry_type></additional><is_claimable>false</is_claimable><name>Pharmacological Clearance of Senescent Cells Alleviates Bone Marrow Aging</name><description>Aging of the hematopoietic system impairs HSC function and alters bone marrow niche behavior, increasing susceptibility to anemia, infections, and hematologic malignancies. Here, we employed the novel BCL-xL/BCL-2-targeted senolytic 753b to pharmacologically clear senescent cells in aged animals, evaluating its safety, efficacy, and restorative benefits to hematopoiesis.</description><dates><publication>2026/09/25</publication></dates><accession>GSE316278</accession><cross_references><GSM>GSM9448780</GSM><GSM>GSM9448787</GSM><GSM>GSM9448786</GSM><GSM>GSM9448785</GSM><GSM>GSM9448784</GSM><GSM>GSM9448783</GSM><GSM>GSM9448782</GSM><GSM>GSM9448781</GSM><GPL>24247</GPL><GSE>316278</GSE><taxon>Mus musculus</taxon><PMID>[42523366]</PMID></cross_references></HashMap>