{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316305/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316305"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Myeloid-derived WNTs impairs anti-tumor immune responses in pancreatic cancer","description":"We performed single-cell RNA sequencing on tumor-infiltrating cells isolated from orthotopic KPC pancreatic tumors at day 21 post-implantation. The objective was to determine how macrophage-specific ablation of WNT secretion (Csf1r-Cre;Porcnfl/fl) reshapes the PDAC immune microenvironment.","dates":{"publication":"2026/05/04"},"accession":"GSE316305","cross_references":{"GSM":["GSM9449272","GSM9449271"],"GPL":["24247"],"GSE":["316305"],"taxon":["Mus musculus"]}}