{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316584/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316584"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"MicroRNA-224 Orchestrates the BMP Pathway and Represents a New Therapeutic Target for Pulmonary Arterial Hypertension","description":"Mice were maintained under hypoxic conditions for 3 weeks with weekly Sugen injections and were then randomized to receive an intratracheal injection of a chemically modified antisense oligonucleotide targeting miR-224 (LNA-224) or a control antimiR (LNA-Ctrl; 5 mg/kg each) at week 3. A separate group of mice was maintained under normoxic conditions and received an intratracheal injection of LNA-Ctrl at week 3 (Nox). All mice were sacrificed at week 6, and scRNA-seq analyses were performed.","dates":{"publication":"2026/04/03"},"accession":"GSE316584","cross_references":{"GSM":["GSM9456515","GSM9456516","GSM9456511","GSM9456512","GSM9456513","GSM9456514","GSM9456510","GSM9456508","GSM9456509"],"GPL":["34328"],"GSE":["316584"],"taxon":["Mus musculus"]}}