{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316783/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316783"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Whole-genome microarray profiling of nutrient-deprived medium (NDM) in human PANC-1 pancreatic cancer cells","description":"Pancreatic ductal adenocarcinoma cells often encounter nutrient deprivation in the tumor microenvironment and are thought to adapt by altering the expression of multiple genes. However, comprehensive time-resolved profiling of transcriptional responses under nutrient-deprived conditions remains limited. Here, we performed whole-genome microarray expression profiling to characterize gene expression changes in the human pancreatic cancer cell line PANC-1 cultured in nutrient-deprived medium. The dataset captures dynamic nutrient stress–associated gene sets and metabolic remodeling, including induction of genes linked to pentose phosphate pathway–related adaptation (e.g., TKTL1). This dataset provides a resource for studying transcriptional dynamics underlying pancreatic cancer cell survival under nutrient deprivation.","dates":{"publication":"2026/07/30"},"accession":"GSE316783","cross_references":{"GSM":["GSM9460214","GSM9460225","GSM9460224","GSM9460223","GSM9460222","GSM9460221","GSM9460220","GSM9460219","GSM9460218","GSM9460217","GSM9460227","GSM9460216","GSM9460215","GSM9460226"],"GPL":["6480"],"GSE":["316783"],"taxon":["Homo sapiens"]}}