GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316783/primary200OKTranscriptomicsHomo sapiensExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316783GEOGSEfalseWhole-genome microarray profiling of nutrient-deprived medium (NDM) in human PANC-1 pancreatic cancer cellsPancreatic ductal adenocarcinoma cells often encounter nutrient deprivation in the tumor microenvironment and are thought to adapt by altering the expression of multiple genes. However, comprehensive time-resolved profiling of transcriptional responses under nutrient-deprived conditions remains limited. Here, we performed whole-genome microarray expression profiling to characterize gene expression changes in the human pancreatic cancer cell line PANC-1 cultured in nutrient-deprived medium. The dataset captures dynamic nutrient stress–associated gene sets and metabolic remodeling, including induction of genes linked to pentose phosphate pathway–related adaptation (e.g., TKTL1). This dataset provides a resource for studying transcriptional dynamics underlying pancreatic cancer cell survival under nutrient deprivation.2026/07/30GSE316783GSM9460214GSM9460225GSM9460224GSM9460223GSM9460222GSM9460221GSM9460220GSM9460219GSM9460218GSM9460217GSM9460227GSM9460216GSM9460215GSM94602266480316783Homo sapiens