{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316944/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Arabidopsis thaliana"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316944"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Deficiency in plastid EF-Tu elicits DNA damage response in Arabidopsis thaliana","description":"Arabidopsis RAB8D (AT4G20360) encodes the plastid translation factor EF-Tu, which is crucial for plant viability. We wondered about the connection between RAB8D deficiency and DNA damage response. RNA-seq results revealed significant upregulation of DNA repair-related genes in rab8d-2, a knock-down mutant of RAB8D. Introducing the knockout allele of ATM (atm-2), SOG1 (sog1-1), NAC044 (nac044-1), or NAC085 (nac085-1) into rab8d-2 significantly reduced the expression of DNA repair-related genes.","dates":{"publication":"2026/08/04"},"accession":"GSE316944","cross_references":{"GSM":["GSM9462870","GSM9462871","GSM9462860","GSM9462872","GSM9462861","GSM9462862","GSM9462873","GSM9462874","GSM9462863","GSM9462864","GSM9462865","GSM9462866","GSM9462867","GSM9462868","GSM9462857","GSM9462869","GSM9462858","GSM9462859"],"GPL":["31102"],"GSE":["316944"],"taxon":["Arabidopsis thaliana"]}}