{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE317nnn/GSE317299/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE317299"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Distinct Immune Signatures of Steroid Responsiveness in Childhood Nephrotic Syndrome","description":"Idiopathic nephrotic syndrome (INS) is the most common primary glomerular disorder in children, yet the immunopathogenesis underlying steroid responsiveness remains incompletely understood. Here, we applied single-cell RNA sequencing to peripheral blood mononuclear cells obtained from three treatment-naïve children with steroid-sensitive nephrotic syndrome (SSNS) and one child with secondary steroid-resistant nephrotic syndrome (SRNS) at first relapse, all prior to immunosuppressive therapy.","dates":{"publication":"2026/07/01"},"accession":"GSE317299","cross_references":{"GSM":["GSM9468896"],"GPL":["24676"],"GSE":["317299"],"taxon":["Homo sapiens"]}}