{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE317nnn/GSE317310/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":[" Other","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE317310"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"scRNA-seq of bone marrow and splenic emergency granulopoiesis","description":"We performed scRNA-seq analysis using the 10X genomics platform of mice following a model of extramedullary hematopoiesis or control. Here, we isolated bone marrow, spleen and blood Gr1+and cKit+-enriched cells to investigate the dynamics of production across both sites of origin. In addition, we performed the following treatments and blood cells were sorted following similar strategy: (1) Splenectomy: a group of mice was subjected to splenectomy before CPM/AMD treatment; (2) partial irradiation with a shield protecting the abdominal region of the mouse followed by CPM/AMD treatment; (3) Mice treated with CPM/AMD were administered with anti-CXCR2 depleting antibody.","dates":{"publication":"2026/04/17"},"accession":"GSE317310","cross_references":{"GSM":["GSM9469119","GSM9469129","GSM9469128","GSM9469134","GSM9469123","GSM9469122","GSM9469133","GSM9469132","GSM9469121","GSM9469120","GSM9469131","GSM9469127","GSM9469138","GSM9469137","GSM9469126","GSM9469125","GSM9469136","GSM9469135","GSM9469124","GSM9469130"],"GPL":["24247"],"GSE":["317310"],"taxon":["Mus musculus"],"PMID":["[41996475]"]}}