GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE317nnn/GSE317310/primary200OKTranscriptomicsMus musculus OtherExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE317310GEOGSEfalsescRNA-seq of bone marrow and splenic emergency granulopoiesisWe performed scRNA-seq analysis using the 10X genomics platform of mice following a model of extramedullary hematopoiesis or control. Here, we isolated bone marrow, spleen and blood Gr1+and cKit+-enriched cells to investigate the dynamics of production across both sites of origin. In addition, we performed the following treatments and blood cells were sorted following similar strategy: (1) Splenectomy: a group of mice was subjected to splenectomy before CPM/AMD treatment; (2) partial irradiation with a shield protecting the abdominal region of the mouse followed by CPM/AMD treatment; (3) Mice treated with CPM/AMD were administered with anti-CXCR2 depleting antibody.2026/04/17GSE317310GSM9469119GSM9469129GSM9469128GSM9469134GSM9469123GSM9469122GSM9469133GSM9469132GSM9469121GSM9469120GSM9469131GSM9469127GSM9469138GSM9469137GSM9469126GSM9469125GSM9469136GSM9469135GSM9469124GSM946913024247317310Mus musculus[41996475]