{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE317nnn/GSE317314/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE317314"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"RNA-seq of human NK cells that were co-cultured with DU-145 cells, which were pre-treated with hIgG1 isotype, 7C6-hIgG1, or 7C6-GAALIE","description":"7C6 is a monoclonal antibody that inhibits the shedding of MICA and MICB, which are stress-induced ligands often expressed by tumor cells. We developed a new version of 7C6, 7C6-GAALIE, which better binds Fc gamma-activating receptors, and analyzed how it reprograms human NK cell gene expression in vitro after co-culture with a target cell line, DU-145.","dates":{"publication":"2026/03/05"},"accession":"GSE317314","cross_references":{"GSM":["GSM9469152","GSM9469156","GSM9469155","GSM9469154","GSM9469153","GSM9469157"],"GPL":["24676"],"GSE":["317314"],"taxon":["Homo sapiens"],"PMID":["[41999749]"]}}