GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE317nnn/GSE317464/primaryOK200TranscriptomicsDanio rerioExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE317464GEOGSEfalseDiverging routes of oligodendrocyte recruitment in adaptive and regenerative myelinationMyelination by oligodendrocytes is dynamically regulated throughout life, supporting axon and circuit function during development, activity-dependent plasticity and repair after injury. How new oligodendrocytes are recruited from their lifelong pool of oligodendrocyte precursor cells (OPCs) in these distinct contexts remains unclear. We directly compared activity-induced and demyelination-induced oligodendrogenesis under otherwise matched conditions and found that OPCs activated different transcriptional programmes in these different circumstances.2026/02/02GSE317464GSM9472669GSM9472658GSM9472659GSM9472656GSM9472667GSM9472668GSM9472657GSM9472665GSM9472666GSM9472655GSM9472663GSM9472674GSM9472664GSM9472672GSM9472661GSM9472673GSM9472662GSM9472670GSM9472671GSM947266025922317464Danio rerio