GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318188/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318188GEOGSEfalseGDF15 impacts chronic kidney disease and associated cachexia through distinct mechanismsChronic kidney disease (CKD) is frequently accompanied by cachexia and substantial metabolic alterations, including anorexia, muscle/fat wasting, and inflammation, which collectively contribute topoor clinical outcomes.However, the underlying molecular mechanisms remain poorly understood. This study demonstrates that growth differentiation factor 15 (GDF15) plays a pivotal role in CKD-associated cachexia and molecular changes.2026/09/10GSE318188GSM9488803GSM9488802GSM9488801GSM9488800GSM10042233GSM10042234GSM10042235GSM10042236GSM10042237GSM10042238GSM10042239GSM9488795GSM9488811GSM9488810GSM9488799GSM9488798GSM9488797GSM9488796GSM10042244GSM9488809GSM9488808GSM9488807GSM10042240GSM10042241GSM9488806GSM10042242GSM9488805GSM9488804GSM1004224334290318188Mus musculus