GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318190/primaryOK200TranscriptomicsDrosophila melanogasterExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318190GEOGSEfalseThe E-cadherin-Wnt-mir-994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell MaintenanceE-cadherin is encoded by the shg gene and is also expressed in Drosophila ovarian IGS cells. Its knockdown leads to a reduction in GSCs. To investigate the downstream molecular mechanisms and changes in gene expression, we labeled IGS cells with GFP, sorted GFP-positive cells one week after shg knockdown, and performed RNA sequencing. Finally, differential gene expression analysis along with GO and KEGG analyses were conducted.2026/07/08GSE318190GSM9489033GSM9489032GSM9489031GSM9489030GSM9489029GSM948902813304318190Drosophila melanogaster[42359497]