GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318324/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318324GEOGSEfalseTargeted RNA sequencing of resected hepatocellular carcinoma specimens to characterize immune gene expression associated with spatial PD-L1(+) TAM–CD8(+) T cell interactionsThis study investigates immune-related gene expression profiles associated with spatial interactions between PD-L1-positive tumor-associated macrophages (TAMs) and CD8-positive T cells in hepatocellular carcinoma (HCC). RNA was extracted from tumor regions of formalin-fixed paraffin-embedded (FFPE) specimens obtained from eight patients who underwent hepatectomy. Targeted RNA sequencing was performed using custom AmpliSeq panels covering cancer progression– and immunity-related genes. Raw sequencing data and processed gene expression matrices are provided to enable downstream reanalysis.2026/04/30GSE318324GSM9492469GSM9492458GSM9492459GSM9492467GSM9492457GSM9492468GSM9492472GSM9492461GSM9492462GSM9492470GSM9492460GSM9492471GSM9492465GSM9492466GSM9492463GSM949246415520318324Homo sapiens