{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318410/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318410"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"The effects of RBM27 on heart function","description":"The goal of this study is to investigate how RBM27 regulates heart function. Total RNA was extracted using Tripure Isolation Reagent (Roche, Mannheim, Germany) from hearts of Rbm27flox/flox and Rbm27-CKO mice at 12 weeks old. Three independent biological replicates for each group were used for RNA-seq. RNA-seq was performed by deep sequencing using an Illumina Novaseq 6000 platform. Paired-end clean reads were aligned to the mouse reference genome(GRCm38/mm10) with Hisat2 v2.0.5, and the aligned reads were used to quantify mRNA expression by using featureCounts v1.5.0-p3.","dates":{"publication":"2026/08/18"},"accession":"GSE318410","cross_references":{"GSM":["GSM9494024","GSM9494023","GSM9494022","GSM9494027","GSM9494026","GSM9494025"],"GPL":["24247"],"GSE":["318410"],"taxon":["Mus musculus"]}}