{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318669/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Methylation profiling"],"species":["Homo sapiens"],"gds_type":["Methylation profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318669"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Smoking effect on DNA methylation in human blood cell types (1)","description":"Tobacco smoking alters DNA methylation profiles of immune cells which may underpin some of the pathogenesis of smoking-associated diseases. However, approaches linking smoking-driven epigenetic effects in specific immune cell types with disease risk are limited. We isolated six leukocyte subtypes, CD14+ monocytes, CD15+ granulocytes, CD19+ B cells, CD4+ T cells, CD8+ T cells, and CD56+ natural killer cells, from whole blood of healthy adult smokers and nonsmokers for epigenome-wide association study (EWAS).","dates":{"publication":"2026/07/30"},"accession":"GSE318669","cross_references":{"GSM":["GSM9500257","GSM9500256","GSM9500255","GSM9500254","GSM9500253","GSM9500252","GSM9500251","GSM9500250","GSM9500259","GSM9500258","GSM9500291","GSM9500290","GSM9500246","GSM9500289","GSM9500245","GSM9500244","GSM9500288","GSM9500287","GSM9500243","GSM9500242","GSM9500286","GSM9500241","GSM9500285","GSM9500284","GSM9500240","GSM9500283","GSM9500249","GSM9500248","GSM9500247","GSM9500282","GSM9500281","GSM9500280","GSM9500279","GSM9500278","GSM9500277","GSM9500276","GSM9500275","GSM9500274","GSM9500273","GSM9500272","GSM9500239","GSM9500238","GSM9500271","GSM9500270","GSM9500268","GSM9500267","GSM9500266","GSM9500265","GSM9500264","GSM9500263","GSM9500262","GSM9500261","GSM9500269","GSM9500260"],"GPL":["13534"],"GSE":["318669"],"taxon":["Homo sapiens"],"PMID":["[42380929]"]}}