{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318742/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318742"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Cellular Landscape During Ovalbumin-Induced Allergic Lung Inflammation [scRNA-Seq]","description":"Cyclooxygenase-2 (COX-2) is a critical enzyme that helps regulate allergic responses by converting arachidonic acid (AA) into lipid-based compounds called prostaglandins (PGs), which play a key role in maintaining lung function. To better understand how COX-2-derived PGs influence allergic reactions in allergic lung inflammation, we analyzed transcriptomic changes in wild-type (COX-2+/+) and COX-2-/- mice sensitized with the allergen ovalbumin (OVA) using single-cell RNA sequencing","dates":{"publication":"2026/09/11"},"accession":"GSE318742","cross_references":{"GSM":["GSM9501965","GSM9501966","GSM9501967","GSM9501968"],"GPL":["24247"],"GSE":["318742"],"taxon":["Mus musculus"]}}