{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318797/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Mus musculus"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318797"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"CosMX spatial transcriptomics of mouse subcutaneous EO771 tumors to study synergistic effects of NEDD8 depletion and anti-PD-1 therapy","description":"We have established the phenotype that depletion of NEDD8 in tumor cell has synergestic effect with anti-PD1 therapy in mouse EO771 subcutaneous tumor model. In this study we performed CosMX spatial transcriptomics of mouse tumor samples to study the tumor intrinsic and immune environment changes that could explain the outcome.","dates":{"publication":"2026/02/09"},"accession":"GSE318797","cross_references":{"GSM":["GSM9503425","GSM9503424"],"GPL":["36279"],"GSE":["318797"],"taxon":["Mus musculus"]}}