{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319374/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319374"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"RNA-seq profiling of post-hypoxic head and neck cancer cell lines","description":"Hypoxia is an important cause of radiotherapy resistance in head and neck squamous cell carcinoma (HNSCC). To investigate the transcriptional expression associated with post-hypoxic survival, we performed RNA-seq profiling of HPV-negative (FADU) and HPV-positive (SCC154) hypoxia-fate-mapped cell lines, hereafter called FADU-hfm and SCC154-hfm. Non-hypoxic (DsRed-positive) and post-hypoxic (GFP-positive) cells were sorted from 3D hfm-spheroids using fluorescence-activated cell sorting (FACS) and analyzed under normoxic conditions. The resulting dataset provides gene expression profiles of non-hypoxic and post-hypoxic cells.","dates":{"publication":"2026/07/01"},"accession":"GSE319374","cross_references":{"GSM":["GSM9516824","GSM9516813","GSM9516825","GSM9516814","GSM9516815","GSM9516826","GSM9516827","GSM9516816","GSM9516817","GSM9516828","GSM9516818","GSM9516819","GSM9516820","GSM9516821","GSM9516822","GSM9516811","GSM9516812","GSM9516823"],"GPL":["30173"],"GSE":["319374"],"taxon":["Homo sapiens"],"PMID":["[41972846]"]}}