{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319443/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319443"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"RNA-seq profiling of SOX10 knockout A375 melanoma cells","description":"SOX10 is a lineage-defining transcription factor that regulates melanocyte identity and melanoma cell states. To investigate the transcriptional consequences of SOX10 loss, we performed bulk RNA sequencing (RNA-seq) in A375 melanoma cells with SOX10 knockout and matched control cells. This dataset enables analysis of gene expression changes associated with SOX10 depletion and provides a resource for studying the role of SOX10 in regulating melanoma transcriptional programs and cell state transitions.","dates":{"publication":"2026/04/29"},"accession":"GSE319443","cross_references":{"GSM":["GSM9518074","GSM9518073","GSM9518076","GSM9518075","GSM9518078","GSM9518077"],"GPL":["34295"],"GSE":["319443"],"taxon":["Homo sapiens"]}}