GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319443/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319443GEOGSEfalseRNA-seq profiling of SOX10 knockout A375 melanoma cellsSOX10 is a lineage-defining transcription factor that regulates melanocyte identity and melanoma cell states. To investigate the transcriptional consequences of SOX10 loss, we performed bulk RNA sequencing (RNA-seq) in A375 melanoma cells with SOX10 knockout and matched control cells. This dataset enables analysis of gene expression changes associated with SOX10 depletion and provides a resource for studying the role of SOX10 in regulating melanoma transcriptional programs and cell state transitions.2026/04/29GSE319443GSM9518074GSM9518073GSM9518076GSM9518075GSM9518078GSM951807734295319443Homo sapiens