{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319481/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Mus musculus"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319481"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Sodium Channel Isoform Diversity Underlies Chamber-Specific Cardiac Excitability [Spatial Transcriptomics]","description":"Sodium channels are essential for cardiac conduction and excitability. The sodium current is primarily carried by the voltage gated sodium channel isoform NaV1.5. Using a novel NaV1.5 chimeric construct, our study reveals a unique chamber-specific distribution of non-NaV1.5 sodium channel isoforms, and we performed spatial sequencing of murine hearts to assess the transcriptional changes associated with our chimeric channel.","dates":{"publication":"2026/04/09"},"accession":"GSE319481","cross_references":{"GSM":["GSM9518461","GSM9518460","GSM9518462","GSM9518458","GSM9518457","GSM9518459"],"GPL":["34290"],"GSE":["319481"],"taxon":["Mus musculus"],"PMID":["[41878815]"]}}