{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319694/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319694"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Myeloid Piezo1 Drives Cardiac Repair Through Orai1–Rac1-Dependent Efferocytosis","description":"Monocytes/macrophages orchestrate myocardial remodeling through efferocytosis post-myocardial infarction (MI). While the mechanosensitive channel Piezo1 is known to modulate calcium influx in cardiac and immune contexts, its myeloid-specific role in post-infarction healing remains elusive. Single cell RNA sequencing at 3 days post-MI revealed that the efferocytosis-associated genes were upregulated in Piezo1∆LysM group, which serve as a cardioprotective role.","dates":{"publication":"2026/05/27"},"accession":"GSE319694","cross_references":{"GSM":["GSM9523850","GSM9523851","GSM9523847","GSM9523846","GSM9523849","GSM9523848","GSM9523843","GSM9523842","GSM9523845","GSM9523844"],"GPL":["24247"],"GSE":["319694"],"taxon":["Mus musculus"]}}