GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319793/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319793GEOGSEfalseDrug-seq analysis of adult T-cell leukemia cells treated with fluorouracil and bleomycinAdult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy that develops in a subset of individuals infected with human T-lymphotropic virus type 1 (HTLV-1) and is characterized by marked chemoresistance and frequent relapse. HTLV-1 preferentially infects CD4⁺ T cells, which constitute the main malignant population in ATL. We evaluated transcriptomic perturbations in CD4⁺ T cells from five ATL patients, three healthy donors, and two ATL cell lines following 48-hour treatment with the chemotherapeutic agents fluorouracil and bleomycin sulfate.2026/09/09GSE319793GSM952645134295319793Homo sapiens