{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE320nnn/GSE320506/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE320506"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic profiling of HaCaT cells after 24-hour exposure to Fusobacterium nucleatum-derived outer membrane vesicles","description":"Fusobacterium nucleatum is an anaerobic Gram-negative bacterium implicated in mucosal inflammatory conditions. Outer membrane vesicles (OMVs) derived from Gram-negative bacteria are recognized as important mediators of host–microbe interactions. In this study, bulk RNA sequencing was performed to investigate global gene expression changes in HaCaT human keratinocytes following 24-hour treatment with F.n-OMVs (10 μg/mL). The dataset provides transcriptomic profiles of treated and untreated cells and serves as a resource for exploring host cellular responses to bacterial vesicles.","dates":{"publication":"2026/05/15"},"accession":"GSE320506","cross_references":{"GSM":["GSM9544609","GSM9544612","GSM9544613","GSM9544610","GSM9544611","GSM9544614"],"GPL":["34284"],"GSE":["320506"],"taxon":["Homo sapiens"],"PMID":["[42048970]"]}}