GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE322nnn/GSE322523/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE322523GEOGSEfalseMouse heart RNA-seq in isoproterenol (ISO) injury model with or without polystyrene nanoplastics co-exposureMale C57BL/6 mice were assigned to three groups (n=6 per group): ISO, ISO+100 nm polystyrene nanoplastics (PS), and ISO+1 µm PS. Hearts were collected at the study endpoint and profiled by bulk mRNA-seq to identify transcriptional signatures associated with PS size in the setting of ISO-induced myocardial injury. Libraries were prepared and sequenced in two batches (Batch 1 by Novogene; Batch 2 by Majorbio Bio-Pharm Technology).2026/03/28GSE322523GSM9553615GSM9553614GSM9553625GSM9553624GSM9553613GSM9553612GSM9553623GSM9553611GSM9553622GSM9553610GSM9553621GSM9553620GSM9553609GSM9553608GSM9553619GSM9553618GSM9553617GSM955361624247322523Mus musculus