GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE323nnn/GSE323356/primaryOK200GenomicsHomo sapiensGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE323356GEOGSEfalseProtocol for Robust Genomic Mapping of Chromatin Targets Using High-Throughput CUT&RUNThe genomic distribution of proteins that define chromatin state including transcription factors, chromatin modifiers and histone modifications, is critical for understanding gene regulation, cellular identity, and disease development. CUT&RUN assay is a powerful tool for high-resolution genomic mapping of factors that define the epigenome. Here, we present a high-throughput CUT&RUN protocol performed in 96-well plate format, from targeted DNA enrichment to high-quality library preparation, enabling reproducible, efficient, and robust genomic mapping of protein of interests and epigenomic profiling.2026/07/08GSE323356GSM9564249GSM9564247GSM9564248GSM9564246GSM9564254GSM9564252GSM9564253GSM9564250GSM956425124676323356Homo sapiens[42364106]