{"database":"GEO","file_versions":[],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324204"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Mitochondrial Iron Sensitizes Senescent Cancer Cells to Ferroptosis","description":"The chemotherapy regimen FOLFIRINOX has been shown to induce senescence in pancreatic ductal adenocarcinoma (PDAC) cells, as well as in immortalized normal human pancreatic ductal epithelium (HPNE-hTERT) cells. To investigate the transcriptional changes associated with treatment-induced senescence in non-malignant cells, RNA sequencing was performed on HPNE-hTERT cells that were either untreated (vehicle control) or treated with FOLFIRINOX for 4 days.","dates":{"publication":"2026/06/01"},"accession":"GSE324204","cross_references":{"GSM":["GSM9571054","GSM9571049","GSM9571052","GSM9571053","GSM9571050","GSM9571051"],"GPL":["24676"],"GSE":["324204"],"taxon":["Homo sapiens"]}}