{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324382/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Streptococcus pyogenes"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324382"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effect of lipids on Streptococcus pyogenes gene expression","description":"Free fatty acids (FA) secreted by the sebaceous glands are a critical component of the skin barrier. Here, we investigate the activity of the major FA species present in the skin against Streptococcus pyogenes (group A Streptococcus; GAS), a major cause of skin infections such as impetigo, erysipelas, cellulitis, and necrotizing fasciitis. Several relevant FAs had antimicrobial activity against GAS and induced differential regulation of GAS virulence factors.","dates":{"publication":"2026/08/25"},"accession":"GSE324382","cross_references":{"GSM":["GSM9574725","GSM9574726","GSM9574727","GSM9574728"],"GPL":["19982"],"GSE":["324382"],"taxon":["Streptococcus pyogenes"]}}