GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324382/primaryOK200TranscriptomicsStreptococcus pyogenesExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324382GEOGSEfalseEffect of lipids on Streptococcus pyogenes gene expressionFree fatty acids (FA) secreted by the sebaceous glands are a critical component of the skin barrier. Here, we investigate the activity of the major FA species present in the skin against Streptococcus pyogenes (group A Streptococcus; GAS), a major cause of skin infections such as impetigo, erysipelas, cellulitis, and necrotizing fasciitis. Several relevant FAs had antimicrobial activity against GAS and induced differential regulation of GAS virulence factors.2026/08/25GSE324382GSM9574725GSM9574726GSM9574727GSM957472819982324382Streptococcus pyogenes