GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324594/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324594GEOGSEfalseTranscriptomic changes in primary human keratinocytes following exposure to lamotrigine, lamotrigine-N2-oxide, lamotrigine in combination with valproic acid or interferon-γ, and interferon-γ aloneBulk RNA sequencing with differential expression analysis was used to examine transcriptional changes in keratinocytes after exposure to lamotrigine (LTG), its CYP-mediated metabolite LTG-N2-oxide, and co-incubated LTG with valproic acid (VPA). IFN-γ served as a positive control, as its effects on keratinocytes are well documented.2026/03/30GSE324594GSM9579959GSM9579957GSM9579958GSM9579977GSM9579955GSM9579956GSM9579953GSM9579975GSM9579976GSM9579954GSM9579973GSM9579951GSM9579974GSM9579952GSM9579971GSM9579972GSM9579950GSM9579970GSM9579948GSM9579949GSM9579968GSM9579946GSM9579969GSM9579947GSM9579966GSM9579944GSM9579945GSM9579967GSM9579942GSM9579964GSM9579965GSM9579943GSM9579962GSM9579963GSM9579960GSM957996124676324594Homo sapiens[41910223]