GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324814/primaryOK200OtherMus musculusOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324814GEOGSEfalseSpatial transcriptomics dissects mechanism of action of the PD-1 targeted IL15-mutein in B16-F10-OVA tumor-bearing miceKD050 is an anti-PD-1/IL-15 bi-functional antibody with strong PD-1 antagonist function, but lower lymphocyte stimulation enabled by a novel mutation on the IL-15. Here, we spatially characterized at RNA level the effect of mKD050 surrogate I in B16-OVA (melanoma) mouse model, in comparison with anti-mPD1 and mouse non-targetKD050 (mntKD050).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 musculus