{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324892/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":[" Mus musculus","Homo sapiens"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324892"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Systematic Benchmarking of CUT&Tag Improves the Reliability and Reproducibility of Chromatin Analysis II","description":"Cleavage under target and tagementation (CUT&Tag) is a widely used assay for analyzing epigenomic localization of proteins and histone PTMs. This study is focused on increasing the reproducibility of CUT&Tag through standardization of both wet bench and downstream data analysis. We find that 10K cells is the minimum input requirement for robust genome-wide profiling of H3K27ac, H3K9me3, H3K4me3, and H3K36me3 in mESCs cells.","dates":{"publication":"2026/07/16"},"accession":"GSE324892","cross_references":{"GSM":["GSM9588456","GSM9588457","GSM9588458","GSM9588459","GSM9588474","GSM9588452","GSM9588453","GSM9588475","GSM9588476","GSM9588454","GSM9588455","GSM9588470","GSM9588471","GSM9588472","GSM9588450","GSM9588451","GSM9588473","GSM9588449","GSM9588445","GSM9588467","GSM9588468","GSM9588446","GSM9588447","GSM9588469","GSM9588448","GSM9588463","GSM9588442","GSM9588464","GSM9588465","GSM9588443","GSM9588444","GSM9588466","GSM9588460","GSM9588461","GSM9588462"],"GPL":["34284","34290"],"GSE":["324892"],"taxon":[" Mus musculus","Homo sapiens"],"PMID":["[42285100]"]}}