GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324997/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324997GEOGSEfalseHepatocytes promote liver metastasis of pancreatic cancer by providing exogenous serine, 2.The liver is the major site of metastasis for pancreatic ductal adenocarcinoma (PDAC). In this work, we describe a mechanism wherein serine sythensis is essential for PDAC liver metastasis. To describe this, we knocked out Phgdh in mouse KPC cells and then co-cultured the cells with mouse hepatocytes.2026/07/28GSE324997GSM9590343GSM9590344GSM9590352GSM9590341GSM9590342GSM9590350GSM9590340GSM9590349GSM9590338GSM9590339GSM9590347GSM9590336GSM9590348GSM9590337GSM9590345GSM959034624247324997Mus musculus[42778596]