{"database":"GEO","file_versions":[],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE325086"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Ceramide-induced Endoplasmic Reticulum Stress as a Targetable Vulnerability in Endocrine Therapy-Resistant Breast Cancer","description":"10 µM C8-ceramide treated to endocrine therapy (ET) sensitive parental MCF-7 cells along with three of its ET-resistant derivative cell lines (MCF-7-HER2, MCF-7-TAMR, and MCF-7-FULR) for 24 hours. Total RNAseq was performed on triplicate samples from each group to compare C8-ceramide actions in ET-sensitive and ET-resistant breast cancer cells.","dates":{"publication":"2026/05/15"},"accession":"GSE325086","cross_references":{"GSM":["GSM9595721","GSM9595710","GSM9595720","GSM9595723","GSM9595712","GSM9595722","GSM9595711","GSM9595703","GSM9595725","GSM9595714","GSM9595724","GSM9595713","GSM9595702","GSM9595716","GSM9595705","GSM9595715","GSM9595704","GSM9595718","GSM9595707","GSM9595706","GSM9595717","GSM9595709","GSM9595719","GSM9595708"],"GPL":["24676"],"GSE":["325086"],"taxon":["Homo sapiens"]}}