{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE325nnn/GSE325134/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Bos taurus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE325134"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomics signatures Associated with Pregnancy Status in Beef Heifers","description":"Fertility is a multifactorial trait and a key determinant of productivity and sustainability in beef cattle production. Identifying molecular mechanisms and biomarkers associated with fertility could improve the prediction of reproductive potential in beef heifers. Herein, using transcriptomic data from peripheral white blood cells (PWBCs) collected before the time of artificial insemination (AI), we investigated molecular differences between fertile and subfertile beef heifers (n = 6 per group) classified based on their reproductive outcomes. RNA-Sequencing identified 230 differentially expressed genes (DEGs; P ≤ 0.05 and |log2FC| > 0.5) between groups. Over-representation analyses revealed that these molecules were associated with cell cycle regulation, metabolism, and immune-related pathways, including chemokine and JAK-STAT signaling.","dates":{"publication":"2026/04/30"},"accession":"GSE325134","cross_references":{"GSM":["GSM9596564","GSM9596563","GSM9596566","GSM9596565","GSM9596568","GSM9596567","GSM9596569","GSM9596571","GSM9596570","GSM9596573","GSM9596562","GSM9596572"],"GPL":["35143"],"GSE":["325134"],"taxon":["Bos taurus"],"PMID":["[42083569]"]}}