{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE325nnn/GSE325196/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Homo sapiens"],"gds_type":[" Expression profiling by high throughput sequencing","Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE325196"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single Nuclei and Spatial Transcriptomic Datasets in Brain Metastases","description":"We performed single nuclei and spatial transcriptomic sequencing on a cohort of solid tumor human brain metastasis specimens resected at Duke University Medical Center from 1998 to 2022. This includes 23 single nuclei specimens, 12 Visium standard specimens, and 4 Xenium specimens. These samples encompass metastases from lung cancer, breast cancer, melanoma, and sarcoma primaries. Analysis of these data revealed novel tumor-microenvironment cell-cell interactions associated with patient survival.","dates":{"publication":"2026/05/23"},"accession":"GSE325196","cross_references":{"GSM":["GSM9597721","GSM9597720","GSM9597723","GSM9597722","GSM9597725","GSM9597703","GSM9597702","GSM9597724","GSM9597716","GSM9597715","GSM9597718","GSM9597717","GSM9597719","GSM9597730","GSM9597732","GSM9597710","GSM9597731","GSM9597734","GSM9597712","GSM9597711","GSM9597733","GSM9597714","GSM9597736","GSM9597735","GSM9597713","GSM9597705","GSM9597727","GSM9597726","GSM9597704","GSM9597729","GSM9597707","GSM9597728","GSM9597706","GSM9597709","GSM9597708"],"GPL":["24676"],"GSE":["325196"],"taxon":["Homo sapiens"]}}