GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE325nnn/GSE325258/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE325258GEOGSEfalseResidual p53 in HPV positive cervical cancer cells has gain of function propertiesHuman papillomavirus (HPV)-positive cervical cancer cells retain residual p53 despite E6-mediated degradation. To investigate whether this residual p53 has gain-of-function properties, CRISPR/Cas9 was used to generate p53 knockout HeLa clones and compare them with a WT control clone. RNA-seq profiling identified transcriptomic changes associated with loss of residual p53.2026/05/13GSE325258GSM9598554GSM9598555GSM9598552GSM9598553GSM9598550GSM959855124676325258Homo sapiens