GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE325nnn/GSE325262/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE325262GEOGSEfalseTargeting ABL kinases to overcome melanoma immune evasion during MAPKi resistanceWe utilized single-cell sequencing to determine the mechanism by which the ABL1/2 inhibitor, nilotinib, prevents the onset of BRAF/MEK inhibitor resistance. Mice harboring mouse melanomas were treated with BRAF/MEK inhibitors or BRAF/MEK inhibitors plus nilotinib for 4 days, and the resulting tumors were subjected to single-cell RNA-sequencing in order to assess changes in the melanoma and immune populations.2026/07/23GSE325262GSM9598703GSM959870217021325262Mus musculus[42764300]