{"database":"GEO","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Homo sapiens"],"gds_type":["Non-coding RNA profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE325416"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"microRNA expression in patients with pulmonary hypertension due to valve heart disease","description":"To delve deeper into the molecular mechanisms underlying pulmonary hypertension secondary to left heart disease (PH-LHD). In this study, we analyzed microRNA of a unique cohort of patients with persistent PH due to valvular heart disease (PH-VHD) to identify biological pathways associated with disease prognosis. The analysis was performed using the well-characterized SIOVAC (Sildenafil for Improving Outcomes after Valvular Correction) clinical trial cohort. We included 113 patients with demonstrated PH-LHD after valvular correction, and 30 VHD patients with no or mild PH (Control).","dates":{"publication":"2026/03/24"},"accession":"GSE325416","cross_references":{"GSM":["GSM9603010","GSM9603011","GSM9602969","GSM9602966","GSM9602965","GSM9602968","GSM9602967","GSM9602962","GSM9603018","GSM9602961","GSM9603019","GSM9602964","GSM9603016","GSM9603017","GSM9602963","GSM9603014","GSM9603015","GSM9602960","GSM9603012","GSM9603013","GSM9603000","GSM9602959","GSM9602958","GSM9602955","GSM9602954","GSM9602957","GSM9603009","GSM9602956","GSM9602951","GSM9603007","GSM9603008","GSM9602950","GSM9603005","GSM9602953","GSM9603006","GSM9602952","GSM9603003","GSM9603004","GSM9603001","GSM9603002","GSM9603070","GSM9603071","GSM9602948","GSM9602947","GSM9602949","GSM9602944","GSM9602943","GSM9602946","GSM9602945","GSM9602940","GSM9602942","GSM9602941","GSM9603065","GSM9603066","GSM9603063","GSM9603064","GSM9603061","GSM9603062","GSM9603060","GSM9602937","GSM9602936","GSM9602939","GSM9602938","GSM9602933","GSM9602932","GSM9602935","GSM9602934","GSM9602931","GSM9602930","GSM9603069","GSM9603067","GSM9603068","GSM9603054","GSM9603055","GSM9603052","GSM9603053","GSM9603050","GSM9603051","GSM9603058","GSM9603059","GSM9603056","GSM9603057","GSM9603043","GSM9603044","GSM9603041","GSM9603042","GSM9603040","GSM9602999","GSM9602998","GSM9602995","GSM9602994","GSM9602997","GSM9603049","GSM9602996","GSM9602991","GSM9603047","GSM9603048","GSM9602990","GSM9603045","GSM9602993","GSM9603046","GSM9602992","GSM9603032","GSM9603033","GSM9603030","GSM9603031","GSM9602988","GSM9602987","GSM9602989","GSM9602984","GSM9602983","GSM9602986","GSM9603038","GSM9602985","GSM9603039","GSM9602980","GSM9603036","GSM9603037","GSM9602982","GSM9603034","GSM9603035","GSM9602981","GSM9603021","GSM9603022","GSM9603020","GSM9602977","GSM9602976","GSM9602979","GSM9602978","GSM9603029","GSM9602973","GSM9602972","GSM9602975","GSM9603027","GSM9603028","GSM9602974","GSM9603025","GSM9603026","GSM9602971","GSM9603023","GSM9603024","GSM9602970"],"GPL":["24676"],"GSE":["325416"],"taxon":["Homo sapiens"]}}