{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE326nnn/GSE326063/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Homo sapiens"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE326063"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Epigenomic changes in chromatin accessibility following 1,25-dihydroxyvitamin D3 treatment in human endometrial stromal cells","description":"Chromatin accessibility is a key determinant of gene regulation and cellular responsiveness to hormonal signaling. Although vitamin D has been implicated in diverse biological processes, its effects on chromatin accessibility in human endometrial stromal cells remain incompletely characterized. In this study, the impact of 1,25-dihydroxyvitamin D₃ on chromatin accessibility was examined using ATAC-seq. Overall, these findings indicate that 1,25-dihydroxyvitamin D₃ is associated with changes in chromatin accessibility in human endometrial stromal cells and suggest a potential epigenomic basis for vitamin D–mediated cellular responses.","dates":{"publication":"2026/08/12"},"accession":"GSE326063","cross_references":{"GSM":["GSM9621534","GSM9621533","GSM9621536","GSM9621535","GSM9621532","GSM9621531"],"GPL":["18573"],"GSE":["326063"],"taxon":["Homo sapiens"],"PMID":["[42146510]"]}}