GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE326nnn/GSE326369/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE326369GEOGSEfalseONX-0914 Ameliorates Hepatic Steatosis in MASLD by Stabilizing HDAC2 and Inhibiting SREBP1 Acetylation via PSMB8 InhibitionTo investigate the mechanism by which ONX‑0914 ameliorates MASLD, HFD‑fed mice were randomized to receive the selective PSMB8 inhibitor ONX‑0914 (10 mg/kg in 10% captisol, s.c., every other day) or vehicle control for an additional 6 weeks while remaining on the HFD. At the experimental endpoint, liver tissues were collected for RNA sequencing.2026/04/02GSE326369GSM9629950GSM9629949GSM9629948GSM9629945GSM9629947GSM962994624247326369Mus musculus