GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE326nnn/GSE326591/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE326591GEOGSEfalseTranscriptomic profiling of pancreatic islets in mice with ALIX deletion in PDGFRα⁺ mesenchymal progenitors under high-fat diet feedingUsing mice in which ALIX, a key regulator of small extracellular vesicle (sEV) biogenesis, was selectively deleted in PDGFRα⁺ mesenchymal progenitors (Pα-ALIXKO mice), we performed RNA sequencing of pancreatic islets isolated from control and Pα-ALIXKO mice under high-fat diet feeding. This dataset enables the analysis of transcriptomic changes in pancreatic islets derived from control and Pα-ALIXKO mice.2026/08/31GSE326591GSM9635160GSM9635162GSM9635161GSM9635164GSM9635163GSM9635166GSM9635165GSM9635168GSM963516724247326591Mus musculus