{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE327nnn/GSE327270/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Methylation profiling"],"species":["Homo sapiens"],"gds_type":["Methylation profiling by genome tiling array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327270"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Semaglutide Slows Epigenetic Aging in a Randomized Trial of HIV-Associated Lipohypertrophy","description":"Genome-wide DNA methylation profiling of PBMC samples from people living with HIV HIV-1 infection impacts biological aging, and epigenetic clocks highlight epigenetic age acceleration in people with HIV. Despite evidence indicating Glucagon-like peptide-1 receptor agonist in beneficial HIV-associated cardiometabolic outcomes, effects on aging biomarkers in HIV epigenetic studies is a major gap in knowledge. Hence, we generated a representative epigenetic dataset to examine Glucagon-like peptide-1 receptor agonist in epigenetic ageing and relationships to clinical phenotypes.","dates":{"publication":"2026/04/17"},"accession":"GSE327270","cross_references":{"GSM":["GSM9652617","GSM9652618"],"GPL":["33022"],"GSE":["327270"],"taxon":["Homo sapiens"]}}