GEOTranscriptomicsHomo sapiens Genome binding/occupancy profiling by high throughput sequencingExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327406GEOGSEfalseSpatially resolved, integrated single-cell multiomic profiling of the transcriptome and epigenomic targets in frozen tissue sectionsWe present a spatial Trekker–CUT&Tag multiome protocol that combines direct spatial barcoding of a frozen tissue section with subsequent single-cell multiome analysis. This approach enables integrated single-cell and spatial profiling of histone H3K27ac modification and gene expression, revealing mechanistic and anatomical cell-type organization across the tissue.2026/05/31GSE327406GSM9656413GSM9656412GSM965641434281327406Homo sapiens