{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE327nnn/GSE327719/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327719"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Estrogen deprivation alters gingival and dentoalveolar complex transcriptomes during ligature-induced periodontitis in mice","description":"Bulk RNA sequencing was performed to investigate estrogen-responsive transcriptomic changes during ligature-induced periodontitis in female C57BL/6J mice. Gingiva and dentoalveolar complex tissues were collected from sham-operated, ovariectomized, and estrogen-replaced ovariectomized mice following ligature-induced periodontitis. Differential expression and pathway analyses were used to identify estrogen-responsive changes in repair-, stromal-, and immune-related gene programs","dates":{"publication":"2026/05/20"},"accession":"GSE327719","cross_references":{"GSM":["GSM9664153","GSM9664142","GSM9664152","GSM9664141","GSM9664151","GSM9664140","GSM9664150","GSM9664146","GSM9664135","GSM9664145","GSM9664134","GSM9664155","GSM9664144","GSM9664133","GSM9664143","GSM9664132","GSM9664154","GSM9664139","GSM9664149","GSM9664138","GSM9664148","GSM9664137","GSM9664147","GSM9664136"],"GPL":["34475"],"GSE":["327719"],"taxon":["Mus musculus"]}}