GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE327nnn/GSE327719/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327719GEOGSEfalseEstrogen deprivation alters gingival and dentoalveolar complex transcriptomes during ligature-induced periodontitis in miceBulk RNA sequencing was performed to investigate estrogen-responsive transcriptomic changes during ligature-induced periodontitis in female C57BL/6J mice. Gingiva and dentoalveolar complex tissues were collected from sham-operated, ovariectomized, and estrogen-replaced ovariectomized mice following ligature-induced periodontitis. Differential expression and pathway analyses were used to identify estrogen-responsive changes in repair-, stromal-, and immune-related gene programs2026/05/20GSE327719GSM9664153GSM9664142GSM9664152GSM9664141GSM9664151GSM9664140GSM9664150GSM9664146GSM9664135GSM9664145GSM9664134GSM9664155GSM9664144GSM9664133GSM9664143GSM9664132GSM9664154GSM9664139GSM9664149GSM9664138GSM9664148GSM9664137GSM9664147GSM966413634475327719Mus musculus