{"database":"GEO","file_versions":[],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Rattus norvegicus"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327997"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Vitamin C facilitates epidermal keratinization through TET-dependent DNA demethylation in basal keratinocytes","description":"Epidermal keratinization is tightly regulated and associated with epigenetic processes, such as DNA methylation, however, the specific role and mechanisms of TET-mediated DNA demethylation in basal keratinocytes remain unclear. We analyzed Tet2/3 knockdown-induced transcriptional alterations in newborn rat epidermal keratinocytes, assessed global gene expression profiles. (Microarray)","dates":{"publication":"2026/04/19"},"accession":"GSE327997","cross_references":{"GSM":["GSM9670123","GSM9670122"],"GPL":["23040"],"GSE":["327997"],"taxon":["Rattus norvegicus"]}}