GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328037/primaryOK200GenomicsMus musculusGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328037GEOGSEfalseAssay for Transposase-Accessible Chromatin With High-Throughput Sequencing in Mouse BMDMs Following CD74 DeficiencyWe employed ACAT-Seq technology to perform a genome-wide assessment of chromatin accessibility changes following CD74 knockout in mouse bone marrow-derived macrophages (BMDMs), with a focus on alterations in regulatory elements associated with aerobic glycolysis-related genes. On this basis, we further explored the potential molecular mechanisms by which CD74 regulates the aerobic glycolytic metabolic pathway in macrophages, including its impact on the accessibility of key transcription factor binding sites and the activity of associated signaling pathways.2026/04/19GSE328037GSM9670761GSM9670760GSM9670759GSM9670758GSM9670757GSM967075621103328037Mus musculus